佛山大學動物科技學院

高寒講師

學歷學位：博士

政治面貌：群眾

導師類別：

電子郵箱：gh1@fosu.edu.cn

學習與工作經(jīng)歷

2012.09-2017.06 南京農(nóng)業(yè)大學動物醫(yī)學本科
2017.09-2019.06 中國農(nóng)業(yè)大學預防獸醫(yī)學碩士
2020.01-2021.05 伊利諾伊大學厄巴納香檳分校病原生物學 RA
2021.09-2024.06 華南農(nóng)業(yè)大學預防獸醫(yī)學博士
2024.08至今佛山大學動物科技學院講師

研究方向

曾從事非洲豬瘟病毒等動物重大烈性病毒病的基礎理論探索和基于單克隆抗體及深度測序的規(guī)模化豬場傳染病診斷工作。現(xiàn)以輪狀病毒與赤羽病毒為主要研究對象探究病毒-宿主相互作用與調(diào)控等機制。

獲獎及榮譽

教學工作

參與本科生課程《動物行為學》、《動物形態(tài)學實驗技術》

教學及科研項目

1.參研國家重點研發(fā)計劃，瀕危與青藏高原動物的病原譜繪制及重要病原體的流行特征研究，2023-2027，125萬元。

代表性文章

1.Gao H*, Zhao DS*, Li CY, Deng MH, Li G, Chen SF, Zhao MM, Qin LM#, & Zhang KS#. (2025) The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress. Molecules 30(3):503.
2.Gao H, Gu TM, Gao XP, Song ZB, Liu J, Song Y, Zhang GH#, & Sun YK#. (2024) African swine fever virus inhibits stress granules formation and benefit viral replication via elevating intracellular reduced glutathione levels. Veterinary Research 55(1):172.
3.Gao H*, Gao XP*, Liu X, Luo YZ, Zhong JH, Liu J, Yan LL, Wang H, Gong L, Zhang GH, Zheng ZZ#, & Sun YK#. (2024) African swine fever virus maintains de novo global cellular protein synthesis and inhibits stress granules formation via dephosphorylating eIF2α. Veterinary Microbiology 290(4):109988.
4.Gao H*, Di DD*, Wu QW, Li J, Liu X, Xu ZY, Xu SJ, Wu CY, Gong L, Sun YK, Zhang GH, Chen HJ#, & Wang H#. (2024) Pathogenicity and horizontal transmission evaluation of a novel isolated African swine fever virus strain with a three-large-fragment-gene deletion. Veterinary Microbiology 290(14):110002.
5.Gao H*, Chen YJ*, Xu XQ, Xu ZY, Xu SJ, Xing JB, Liu J, Zha YF, Sun YK#, & Zhang GH#. (2022) Comprehensive phylogeographic and phylodynamic analyses of global Senecavirus A. Frontiers in Microbiology 13:980862.
6.Xu ZY*, Gao H*, Kuang QY, Xing JB, Wang ZY, Cao XY, Xu SJ, Liu J, Huang Z, Zheng ZZ, Gong L, Wang H, Shi M#, Zhang GH#, & Sun YK#. (2022) Clinical sequencing uncovers the genomic characteristics and mutation spectrum of the 2018 African swine fever virus in Guangdong, China. Frontiers in Veterinary Science 9:978243.
7.Sun YK*, Xu ZY*, Gao H*, Xu SJ, Liu J, Xing JB, Kuang QY, Chen Y, Wang H#, & Zhang GH#. (2022) Detection of a Novel African Swine Fever Virus with Three Large-Fragment Deletions in Genome, China. Microbiology Spectrum 10:e02155-22.

其他成果

發(fā)明專利：張克山，趙登率，覃麗梅，趙孟孟，高寒，張遠航，李平，于頔浠，王天宇，鄭亞杰，周俊，楊帆，李淦，蔡仕楷，維奈妥拉ABT-199在制備防治輪狀病毒的藥物中的應用，202411438378.X，2025-01-06。